19 May 2013

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New Drug Assignments and Reassignments for 2013

See drug assignments and reassignments for previous years.

(Click on a column heading to re-sort the table.)

Drug Name Active Ingred Mfr Indication Approval Date AHFS Class NDA Chem Type*
Skyla® levonorgestrel Bayer birth control 1/9/2013 68:12 - Contraceptives 5
Uceris® budesonide Santarus ulcerative colitis 1/14/2013 68:04 - Adrenals 5
Zecuity® sumatriptan Nupathe migraine headache 1/17/2013 28:32.28 - Selective Serotonin Agonists 3
Nesina® alogliptin Takeda type 2 diabetes mellitus 1/25/2013 68:20.05 - DPP-4 Inhibitors 1
Oseni® alogliptin; pioglitazone Takeda type 2 diabetes mellitus 1/25/2013 68:20.05 - DPP-4 Inhibitors; 68:20.28 - Thiazolidinediones 1
Kazano® alogliptin; metformin Takeda type 2 diabetes mellitus 1/25/2013 68:20.05 - DPP-4 Inhibitors; 68:20.04 - Biguanides 1
Kynamro® mipomersen Genzyme homozygous familial hyper-cholesterolemia (HoFH) 1/29/2013 24:06.92 - Antilipemic Agents, Miscellaneous 1
Ravicti® glycerol phenylbuterate Hyperion urea cycle disorders (UCDs) 2/1/2013 40:10 - Ammonia Detoxicants 1S
Delzicol® mesalamine Warner Chilcott ulcerative colitis 2/1/2013 56:36 - Anti-inflammatory Agents 3S
Versacloz® clozapine Douglas schizophrenia 2/6/2013 28:16.08.04 - Atypical Antipsychotics 3
Pomalyst® pomalidomide Celgene multiple myeloma 2/8/2013 10:00 - Antineoplastic Agents 1
Kadcyla® ado-trastuzumab emtansine Genentech metastatic HER2 breast cancer 2/22/2013 10:00 - Antineoplastic Agents 1
Stivarga® regorafenib Bayer metastatic colorectal cancer 2/25/2013 10:00 - Antineoplastic Agents 1P
Osphena® ospemifene Shionogi menopausal dyspareunia 2/26/2013 68:16.12 - Estrogen Agonists-Antagonists 1S
Enskyce desogestrel; ethinyl estradiol Lupin birth control 3/7/2013 68:12 - Contraceptives
Lymphoseek® technetium Tc99 tilmanocept Navidea lymph node mapping 3/13/2013 36:68 - Roentgenography 1S
Dotarem® gadoterate meglumine Guerbet for use in MRIs of CNS 3/20/2013 36:68 - Roentgenography 1S
botulism antitoxin heptavalent (equine) Cangene botulism 3/22/2013 80:04 - Serums 1
Tecfidera® dimethyl fumerate Biogen Idec multiple sclerosis 3/27/2013 92:20 - Biologic Response Modifiers 1
Karbinal® ER carbinoxamine Tris seasonal and perennial allergic rhinitis; urticaria; angioedema 3/28/2013 4:04 - First Generation Antihistamines 3S
Jencycla norethindrone Lupin birth control 3/28/2013 68:12 - Contraceptives
Quartette® levonorgestrel; ethinyl estradiol Teva birth control 3/28/2013 68:12 - Contraceptives 5
Invokana® canagliflozin Janssen type 2 diabetes 3/29/2013 68:20.18 - Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors (New class) 1
Prolensa® bromfenac Bausch+Lomb postoperative pain and inflammation after cataract surgery 4/5/2013 52:08.20 - Nonsteroidal Anti-inflammatory Agents 5
Diclegis® doxylamine; pyridoxine Duchesnay morning sickness 4/9/2013 56:22.92 - Antiemetics, Misc 4
Daysee ethinyl estradiol; levonorgestrel Lupin birth control 4/10/2013 68:12 - Contraceptives 3
Sitavig® acyclovir Bioalliance recurrent herpes labialis (cold sores) 4/12/2013 84:04.06 - Antivirals 3S
Simbrinza® brinzolamide; brimonidine Alcon open-angle glaucoma; ocular hypertension 4/19/2013 52:40.04 - α-Adrenergic Agonists; 52:40.12 - Carbonic Anhydrase Inhibitors 4
Minastrin® 24 FE ethinyl estradiol; norethindrone; ferrous fumerate Warner Chilcott birth control 4/19/2013 68:12 - Contraceptives 3
Pirmella 7/7/7 & 1/35 ethinyl estradiol; norethindrone Lupin birth control 4/24/2013 68:12 - Contraceptives 3
Kcentra® prothrombin complex concentrate (human) CSL Behring urgent reversal of VKA (e.g., warfarin) in acute major bleeding episodes 4/29/2013 20:28.16 - Hemostatics
Procysbi® cysteamine bitartrate Raptor nephropathic cystinosis 4/30/2013 92:92 - Other Misc Therapeutic Agents 5
Breo Ellipta® fluticasone / vilanterol Glaxo COPD 5/10/2013 68:04 - Adrenals; 12:12.08.12 - Selective β2-Adrenergic Agonists 1
Xofigo® radium (Ra223) Bayer advanced prostate cancer with metastasis to bone 5/15/2013 78:00 - Radioactive Agents 1P

 

* NDA Chemical Types

Number Meaning
1 New molecular entity (NME)
2 New ester, new salt, or other noncovalent derivative
3 New formulation
4 New combination
5 New manufacturer
6 New indication
7 Drug already marketed, but without an approved NDA
8 OTC (over-the-counter) switch

 

AHFS Classification Changes for 2013

The following table describes changes to the AHFS Pharmacologic-Therapeutic Classification© that will go into effect with the publication of the 2013 edition of AHFS Drug Information® (February 1, 2013), as well as any new classes added after the publication of the 2012 edition. This is only a partial listing of the AHFS PTC. The full classification system, along with a list of drugs covered in AHFS DI and their corresponding classes, is available in the printed edition and is available electronically in a separate file. Please contact the ASHP Marketing and Sales Office for licensing information at 301-664-8757 or marketing@ashp.org.

AHFS Class Retired Change Description
28:20
-
Name Change (Anorexigenic Agents and Respiratory and CNS Stimulants)
28:20.08
-
New classification (Anorexigenic Agents)
28:20.08.04
-
New classification (Amphetamine Derivatives)
28:20.08.32
-
New classification (Selective Serotonin Receptor Agonists)
28:20.32
-
New classification (Respiratory and CNS Stimulants)
28:20.80
-
New classification (Wakefulness-promoting Agents)
28:20.92
-
Name Change (Anorexigenic Agents and Stimulants, Miscellaneous)
48:14
-
New classification (Cystic Fibrosis Transmembrane Conductance Regulator Modulators)
48:14.04
-
New classification (Cystic Fibrosis Transmembrane Conductance Regulator Correctors)
48:14.12
-
New classification (Cystic Fibrosis Transmembrane Conductance Regulator Potentiators)
68:20.18
-
New classification 4/3/2013 (Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors)

 

Drug Reassignments for 2013

Along with the changes to the classification system noted above, the following drugs have been assigned to new classes accordingly:

Drug Name(s) Active Ingred Old AHFS Class New AHFS Class
Tenuate® diethylpropion 28:20.92 28:20.08.04
Adipost®, Bontril® phendimetrazine 28:20.92 28:20.08.04
Adipex®, Ionamin® phentermine 28:20.92 28:20.08.04
Belviq® lorcaserin 28:20.92 28:20.08.32
Amoply® ammonia spirit, aromatic 28:20.92 28:20.32
Cafcit®, No Doz®, Vivarin® caffeine/ caffeine and sodium benzoate 28:20.92 28:20.32
Focalin® dexmethylphenidate 28:20.92 28:20.32
Dopram® doxapram 28:20.92 28:20.32
Concerta®, Daytrana®, Metadate®, Methylin®, Ritalin® methylphenidate 28:20.92 28:20.32
Nuvigil® armodafinil 28:20.92 28:20.80
Provigil® modafinil 28:20.92 28:20.80
Kalydeco® ivacaftor 48:92 48:14.12

 

All material distributed as part of AHFS Drug Information is copyrighted. Reproduction, storage on a retrieval system, or transmission of this material or any part thereof in any form or by any means without the express written permission of the American Society of Health-System Pharmacists is prohibited.

Please contact ASHP eHealth Solutions Division at +1 (301) 664-8647 for more detailed information.