Alerts & Corrections

AHFS Drug Information/Essentials Update – May 2016

The May update to the AHFS Drug Information/Essentials database was published today. Highlights from this month’s update include:

New AHFS/Essentials Monographs

  • Ganciclovir (Zirgan®)
    • The ophthalmic gel is indicated for the topical treatment of acute herpetic keratitis in patients with dendritic ulcers

FDA MedWatch Alerts

  • Metformin
    • Revised warnings in reduced kidney function
  • Fluconazole
    • FDA is evaluating the results of a Danish study that concluded there is a possible increased risk of miscarriage with the use of oral fluconazole for yeast infections
  • Aripiprazole
    • Warning regarding compulsive or uncontrollable urges to gamble, binge eat, shop, and have sex have been reported
  • Ticagrelor and Vortioxetine
    • Brand name change for vortioxetine (Brintellix) due to name confusion with ticagrelor (Brilinta)