The May update to the AHFS Drug Information/Essentials database was published today. Highlights from this month’s update include:
New AHFS/Essentials Monographs
- Ganciclovir (Zirgan®)
- The ophthalmic gel is indicated for the topical treatment of acute herpetic keratitis in patients with dendritic ulcers
FDA MedWatch Alerts
- Metformin
- Revised warnings in reduced kidney function
- Fluconazole
- FDA is evaluating the results of a Danish study that concluded there is a possible increased risk of miscarriage with the use of oral fluconazole for yeast infections
- Aripiprazole
- Warning regarding compulsive or uncontrollable urges to gamble, binge eat, shop, and have sex have been reported
- Ticagrelor and Vortioxetine
- Brand name change for vortioxetine (Brintellix) due to name confusion with ticagrelor (Brilinta)
