The March update to the AHFS Patient Medication Information (PMI) database has been published. Highlights of the update include:

New PMI Monographs

• Hydrocortisone Rectal (Anusol HC^®, Colocort^®, Cortenema^®, Preparation H Anti-Itch^®, Proctocort^®, Proctofoam HC^®)
  • Rectal hydrocortisone is used along with other medications to treat proctitis (swelling in the rectum) and ulcerative colitis (a condition which causes swelling and sores in the lining of the large intestine and rectum).
• Lixisenatide Injection (Adlyxin^®)
  • Lixisenatide injection is used along with diet and exercise to treat type 2 diabetes.
• Cromolyn Ophthalmic (Crolom^®)
  • Cromolyn ophthalmic is used to treat the symptoms of allergic conjunctivitis (a condition in which the eyes become itchy, swollen, red, and teary when they are exposed to certain substances) and keratitis (a condition that causes swelling of the cornea [tissue in the front of the eye] that causes eye redness, pain, and tearing and changes in vision).
• Bezlotoxumab Injection (Zinplava^®)
  • Bezlotoxumab injection is used to decrease the risk of Clostridium difficile infection (a type of bacteria that can cause severe or life-threatening diarrhea) from coming back in people at high risk for C. difficile infection.

FDA MedWatch Alert Revisions

FDA is warning that eluxadoline (Viberzi^®), a medicine used to treat irritable bowel syndrome with diarrhea (IBS-D), should not be used in patients who do not have a gallbladder.